| ADTX 0.0127 -2.31% | SOXS 4.72 -5.03% | SPCX 160.95 19.22% | DFNS 0.233 -9.20% | BITO 8.65 0.12% | RUBI 0.4676 -24.62% | TZA 4.16 -2.58% | CAST 1.55 140.68% | AAL 14.98 2.25% | INTC 124.57 6.51% | SPCE 3.91 -31.76% | SHFS 0.276 16.46% | SRXH 0.148 17.65% | NOK 14.795 5.00% | NVDA 205.19 0.16% | BYAH 1.47 40.00% | SPDN 8.81 -0.45% | TQQQ 77.52 1.99% | TSLL 13.59 3.58% | PAVS 0.208 -28.28% | CPOP 0.195 -81.43% | SMCI 30.46 -4.72% | CUPR 3.97 64.73% | VSME 1.69 52.25% | YYGH 0.119 -3.25% | SQQQ 40.04 -1.93% | RKLB 102.39 -10.79% | TSLA 406.43 1.82% | NVD 5.02 -0.40% | WOK 0.0753 -17.70% | SPY 741.75 0.54% | ASTS 82.41 -15.53% | KEEL 5.59 1.27% | ONDS 9.33 -5.09% | SPYM 87.06 0.25% | AMZN 238.55 -1.23% | XLF 53.34 1.37% | SATS 114.08 -10.97% | QQQ 721.34 0.59% | SOFI 16.58 -0.54% | PLUG 2.76 -2.47% | SOXL 234.68 4.77% | GRAB 3.3 -1.49% | DRIP 4.74 -2.47% | AMC 2.34 2.63% | IREN 59.77 5.40% | HKIT 0.5025 -10.11% | RKLZ 3.01 21.37% | RZLV 2.68 5.93% | MARA 14.08 3.45%

Clearside Biomedical's Financial Performance in the Biopharmaceutical Industry

Clearside Biomedical, Inc. (NASDAQ:CLSD) is a biopharmaceutical company focused on developing therapies to treat eye diseases. The company uses its proprietary SCS Microinjector to deliver drugs to the back of the eye. In the competitive landscape, Clearside competes with other biopharmaceutical companies like Cidara Therapeutics, Selecta Biosciences, vTv Therapeutics, and Corvus Pharmaceuticals.

Clearside Biomedical's ROIC is -177.13%, which is significantly lower than its WACC of 17.35%. This negative ROIC indicates that the company is not generating positive returns on its invested capital. The ROIC to WACC ratio of -10.21 further highlights that Clearside's returns are well below its cost of capital, suggesting inefficiencies in capital utilization.

In comparison, Cidara Therapeutics has a ROIC of -46.99% and a WACC of 10.99%, resulting in a ROIC to WACC ratio of -4.27. While still negative, Cidara's ratio is less severe than Clearside's, indicating relatively better capital efficiency. 

Selecta Biosciences stands out with a positive ROIC of 6.80% and a WACC of 8.38%, resulting in a ROIC to WACC ratio of 0.81. This positive ratio suggests that Selecta is generating returns closer to its cost of capital, making it the best performer in this peer group. Meanwhile, vTv Therapeutics and Corvus Pharmaceuticals also show negative ROIC to WACC ratios of -19.61 and -7.99, respectively, indicating challenges in generating returns above their cost of capital.

Published on: November 21, 2025