| ATPC 0.1253 79.00% | MTEN 0.0327 -7.37% | OCG 0.01 -15.25% | SOXS 2.08 -8.77% | AUID 2.035 105.04% | IVP 0.0515 -37.20% | CJMB 3.5694 218.70% | ZSL 3.045 8.17% | SLV 81.5 -3.62% | NVDA 188.1886 2.76% | APLT 0.1018 1.90% | SPHL 8.9182 296.36% | INTC 48.34 -0.78% | BNKK 4.6418 66.97% | SOXL 60.565 9.36% | TQQQ 55.5586 3.21% | DVLT 0.7554 5.18% | ASST 0.9847 -4.40% | BYND 1.02 6.04% | TSLL 18.48 2.27% | SIDU 3.675 -2.00% | EEM 58.15 0.69% | JTAI 0.4798 5.54% | AMD 236.8512 5.93% | TZA 5.985 -2.84% | TSLS 5.125 -1.25% | ONDS 13.065 -3.65% | MSTX 4.745 -8.75% | PTHL 0.4676 6.32% | NOK 6.6459 4.50% | PCLA 0.2119 -4.12% | TSM 346.17 5.83% | IBRX 3.3386 10.55% | SEGG 1.0804 16.59% | RZLV 4.653 14.61% | VALE 14.675 0.44% | SPY 694.59998 0.61% | GRAB 4.48 -3.24% | IBIT 54.3599 -1.95% | QQQ 626.23 1.08% | BBAI 6.285 0.40% | SQQQ 64.8096 -3.18% | GPUS 0.3055 -4.80% | OCUL 11.05 -0.18% | XLF 54.63 0.89% | CRWV 97.83 8.94% | DUST 5.795 -0.09% | TSLA 444.3829 1.18% | BMNR 31.59 -3.26% | EVTV 3.5233 13.65%

Alector, Inc. (NASDAQ:ALEC) Faces Downgrade Amid Drug Trial Setback

Alector, Inc. (NASDAQ:ALEC) is a biotechnology company focused on developing therapies for neurodegenerative diseases. The company aims to harness the power of the immune system to combat these conditions. Alector faces competition from other biotech firms working on similar treatments, but its unique approach sets it apart in the industry.

On October 22, 2025, William Blair downgraded Alector's stock from "Outperform" to "Market Perform." This change came as ALEC's stock price stood at $3.21. The downgrade reflects concerns about the company's recent challenges, particularly the failure of its experimental drug in a late-stage trial.

Alector's shares have seen a significant decline following the announcement that its drug did not slow the progression of a rare form of dementia. This setback led the company to terminate the study and reduce its workforce by nearly half. The stock price, currently at $3.21, has decreased by 3.02%, with a change of $0.10.

The stock has fluctuated between $3.09 and $3.27 today, highlighting the market's reaction to recent developments. Over the past year, ALEC has experienced a high of $6.14 and a low of $0.87. The company's market capitalization is approximately $324.9 million, indicating its current valuation in the market.

Alector's trading volume on the NASDAQ is 1,393,229 shares, reflecting investor interest and activity. Despite the recent challenges, the company remains focused on its mission to develop innovative therapies for neurodegenerative diseases.

Published on: October 22, 2025